| Control ( | Pre- and post-therapeutic days | |||||
|---|---|---|---|---|---|---|
| At admission (0) | 5 | 10 | 20 | 30 | ||
| CRS | 1.7 ± 0.2 | 5.4 ± 0.2a | 3.8 ± 0.2b | 2.6 ± 0.2c | 1.8 ± 0.2d | 1.5 ± 0.2d |
| ULS | 0.0 ± 0.0 | 3.4 ± 0.3a | 3.2 ± 0.2ab | 2.9 ± 0.3abc | 2.6 ± 0.2bc | 2.3 ± 0.1c |
| RBCs (×1012/L) | 7.8 ± 0.2 | 8.4 ± 0.4 | 8.1 ± 0.3 | 7.8 ± 0.2 | 8.2 ± 0.1 | 8.0 ± 0.1 |
| PCV (%) | 27 ± 1 | 28 ± 0.8 | 29 ± 0.6 | 29 ± 0.7 | 28 ± 0.3 | 29 ± 0.4 |
| Hemoglobin (g/L) | 96 ± 3 | 97 ± 3 | 99 ± 2 | 98 ± 2 | 102 ± 1 | 99 ± 1 |
| WBCs (×109/L) | 7.7 ± 0.4 | 11.7 ± 1a | 10.5 ± 0.9ab | 9.3 ± 0.4b | 8.8 ± 0.2b | 9 ± 0.2b |
| Total proteins (g/L) | 58 ± 1.5 | 66 ± 3 | 65 ± 2 | 63 ± 2 | 62 ± 1 | 63 ± 1 |
| Albumin (g/L) | 26 ± 0.9 | 25 ± 1 | 24 ± 0.9 | 25 ± 0.7 | 26 ± 1.1 | 27 ± 0.6 |
| Globulins (g/L) | 32 ± 1.2 | 41 ± 2 | 41 ± 2 | 38 ± 2 | 36 ± 1 | 36 ± 1 |
| AST (U/L) | 62 ± 6 | 81 ± 5a | 83 ± 3a | 81 ± 3a | 78 ± 3ab | 69 ± 3b |
| GGT (U/L) | 24 ± 1.3 | 23 ± 1.5 | 21 ± 0.9 | 20 ± 0.5 | 22 ± 0.5 | 21 ± 0.5 |
| Arterial blood gas analysis | ||||||
| pH | 7.36 ± 0.01 | 7.33 ± 0.01 | 7.32 ± 0.01 | 7.31 ± 0.02 | 7.32 ± 0.01 | 7.32 ± 0.01 |
| PCO2 (mmHg) | 48 ± 2 | 56 ± 3a | 54 ± 3ab | 51 ± 1ab | 50 ± 2ab | 49 ± 1b |
| PO2 (mmHg) | 88 ± 2 | 58 ± 3b | 66 ± 3ab | 69 ± 2ab | 73 ± 2ab | 75 ± 3a |
| Bicarbonate (mmol/L) | 29 ± 1 | 29 ± 0.8 | 29 ± 0.7 | 28 ± 0.6 | 27 ± 0.6 | 27 ± 0.5 |
| BE (mmol/L) | 2.2 ± 0.5 | −0.7 ± 1.6 | 0.9 ± 0.3 | 0.6 ± 0.3 | 0.8 ± 0.1 | 0.6 ± 0.2 |