Table 2. Effect of flavonoid on blood profile in LPS challenged growing pig

Items Saline LPS SEM p-value
−Fla +Fla −Fla +Fla LPS effect Flavonoid effect Interaction
0 h
 WBC (103/µL) 14.73 14.47 18.50 16.85 0.50 0.4500 0.1483 0.5856
 Lymphocyte (%) 34.34 34.93 38.87 37.39 2.05 0.4944 0.0987 0.3381
 IgG (103/µL) 273 280 315 308 17 0.7645 0.1203 0.5572
 TNF-α (%) 140.4 114.1 144.0 105.0 11.1 0.8355 0.0234 0.6376
 IL6 (%) 80.1 68.4 87.9 77.0 4.9 0.0987 0.0271 0.9281
2 h
 WBC (103/µL) 14.79 17.66 14.76 16.63 0.65 0.4054 0.0012 0.4380
 Lymphocyte (%) 39.17 41.98 43.08 42.45 2.21 0.3797 0.6590 0.4884
 IgG (103/µL) 280 340 281 330 19 0.8435 0.0229 0.8203
 TNF-α (%) 111.3 103.8 107.1 97.9 10.1 0.6908 0.5120 0.9438
 IL6 (%) 83.6 70.2 88.7 80.9 4.6 0.0777 0.0221 0.5207
6 h
 WBC (103/µL) 18.20 17.40 17.02 17.65 0.60 0.4178 0.8844 0.2190
 Lymphocyte (%) 46.16 48.76 46.77 48.09 0.88 0.9739 0.0379 0.4762
 IgG (103/µL) 251 318 245 291 16 0.3076 0.0023 0.5383
 TNF-α (%) 78.7 72.8 82.2 71.1 6.0 0.8908 0.2118 0.6937
 IL6 (%) 75.0 65.3 80.1 73.1 3.9 0.0994 0.0355 0.7181
12 h
 WBC (103/µL) 18.93 18.00 17.65 18.33 0.59 0.3824 0.8129 0.1439
 Lymphocyte (%) 46.70 48.66 46.69 48.77 0.85 0.9500 0.0242 0.9437
 IgG (103/µL) 234 271 237 264 14 0.8739 0.0284 0.7055
 TNF-α (%) 68.2 63.3 71.9 63.9 5.6 0.7278 0.2998 0.7999
 IL6 (%) 67.4 65.9 70.5 67.6 3.9 0.5544 0.5956 0.8688
LPS, lipopolysachharide; −Fla, without flavonoid; +Fla, with 0.1% flavonoid.