Table 2. Effect of flavonoid on blood profile in LPS challenged growing pig
Items | Saline | LPS | SEM | p-value |
−Fla | +Fla | −Fla | +Fla | LPS effect | Flavonoid effect | Interaction |
0 h | | | | | | | | |
WBC (103/µL) | 14.73 | 14.47 | 18.50 | 16.85 | 0.50 | 0.4500 | 0.1483 | 0.5856 |
Lymphocyte (%) | 34.34 | 34.93 | 38.87 | 37.39 | 2.05 | 0.4944 | 0.0987 | 0.3381 |
IgG (103/µL) | 273 | 280 | 315 | 308 | 17 | 0.7645 | 0.1203 | 0.5572 |
TNF-α (%) | 140.4 | 114.1 | 144.0 | 105.0 | 11.1 | 0.8355 | 0.0234 | 0.6376 |
IL6 (%) | 80.1 | 68.4 | 87.9 | 77.0 | 4.9 | 0.0987 | 0.0271 | 0.9281 |
2 h | | | | | | | | |
WBC (103/µL) | 14.79 | 17.66 | 14.76 | 16.63 | 0.65 | 0.4054 | 0.0012 | 0.4380 |
Lymphocyte (%) | 39.17 | 41.98 | 43.08 | 42.45 | 2.21 | 0.3797 | 0.6590 | 0.4884 |
IgG (103/µL) | 280 | 340 | 281 | 330 | 19 | 0.8435 | 0.0229 | 0.8203 |
TNF-α (%) | 111.3 | 103.8 | 107.1 | 97.9 | 10.1 | 0.6908 | 0.5120 | 0.9438 |
IL6 (%) | 83.6 | 70.2 | 88.7 | 80.9 | 4.6 | 0.0777 | 0.0221 | 0.5207 |
6 h | | | | | | | | |
WBC (103/µL) | 18.20 | 17.40 | 17.02 | 17.65 | 0.60 | 0.4178 | 0.8844 | 0.2190 |
Lymphocyte (%) | 46.16 | 48.76 | 46.77 | 48.09 | 0.88 | 0.9739 | 0.0379 | 0.4762 |
IgG (103/µL) | 251 | 318 | 245 | 291 | 16 | 0.3076 | 0.0023 | 0.5383 |
TNF-α (%) | 78.7 | 72.8 | 82.2 | 71.1 | 6.0 | 0.8908 | 0.2118 | 0.6937 |
IL6 (%) | 75.0 | 65.3 | 80.1 | 73.1 | 3.9 | 0.0994 | 0.0355 | 0.7181 |
12 h | | | | | | | | |
WBC (103/µL) | 18.93 | 18.00 | 17.65 | 18.33 | 0.59 | 0.3824 | 0.8129 | 0.1439 |
Lymphocyte (%) | 46.70 | 48.66 | 46.69 | 48.77 | 0.85 | 0.9500 | 0.0242 | 0.9437 |
IgG (103/µL) | 234 | 271 | 237 | 264 | 14 | 0.8739 | 0.0284 | 0.7055 |
TNF-α (%) | 68.2 | 63.3 | 71.9 | 63.9 | 5.6 | 0.7278 | 0.2998 | 0.7999 |
IL6 (%) | 67.4 | 65.9 | 70.5 | 67.6 | 3.9 | 0.5544 | 0.5956 | 0.8688 |
LPS, lipopolysachharide; −Fla, without flavonoid; +Fla, with 0.1% flavonoid.