Table 3. Top significant pathways for the positional candidate genes located within the QTL for meat color (b) and shear force traits in Yorkshire pigs

Traits Pathway p-value1) Genes
b* ECM-receptor interaction < 0.01 IBSP, DMP1, FREM2, DSPP
Folate biosynthesis < 0.05 QDPR, PAH
Hippo signaling pathway < 0.05 DLG2, FZD4, DLG4, BMP5
Vitamin B6 metabolism < 0.05 AOX1
Phenylalanine, tyrosine and tryptophan biosynthesis < 0.05 PAH
Shear Glycosaminoglycan degradation < 0.01 HYAL1, HYAL3
Glycerolipid metabolism < 0.01 DGKB, GPAT3, DGKH
Phosphatidylinositol signaling system < 0.05 DGKB, PIP4K2A, DGKH
Choline metabolism in cancer < 0.05 SLC44A5, DGKB, DGKH
Glycerophospholipid metabolism < 0.05 DGKB, GPAT3, DGKH
ABC transporters < 0.05 ABCA1, ABCC8
Nominal p-value.
QTLs, quantitative trait loci; ECM, extracellular matrix.