Table 11. Metabolites affected by supplementation treatments compared with control

The observed change in the production	D-Met	HMBi
Increase	Serine	Glucose 1-phosphate
	Glutamine	6-Phosphogluconate
	Methionine	Isoleucine
	Aspartate
	Isoleucine
	Leucine
	Tyrosine
Decrease	Uridine monophosphate	Uridine monophosphate
		N-Acetyl-L-glutamate

Metabolite analysis (Bos taurus). Increased and decreased metabolites were further analyzed by Dunnett’s Multiple Comparison test which is a multiple comparison procedure for treatments with a single control.
D-Met, D-methionine; HMBi, 2-hydroxy-4-methylthiobutanoic acid i.