Table 1. Top 10 differentially expressed miRNAs between the two samples in each comparison

Top 10 DEMs of C1		Top 10 DEMs of C2		Top 10 DEMs of C3
Up in HC	Up in HM	Up in JC	Up in JM	Up in JC	Up in HC
bta-miR-15a	bta-miR-29d-3p	bta-miR-101	bta-miR-135a	bta-miR-885	bta-miR-143
bta-miR-222	bta-miR-29b	bta-miR-455-3p	bta-miR-326	bta-miR-1306	bta-miR-2284y
bta-miR-221	bta-miR-3613a	bta-miR-490	bta-miR-2885	bta-miR-23b-5p	bta-miR-30e-5p
bta-miR-30a-5p	bta-miR-885	bta-miR-296-3p	bta-miR-335	bta-miR-3613a	bta-miR-2284x
bta-miR-142-3p	bta-miR-23b-5p	bta-miR-7857	bta-miR-2284x	bta-miR-664b	bta-miR-181c
bta-miR-182	bta-miR-6119-3p	bta-miR-223	bta-miR-2284y	bta-miR-150	bta-miR-769
bta-miR-142-5p	bta-miR-2904	bta-miR-130a	bta-miR-6522	bta-miR-455-3p	bta-miR-6522
bta-miR-3431	bta-miR-1306	bta-miR-671	bta-miR-30e-5p	bta-miR-365-3p	bta-miR-326
bta-miR-320b	bta-miR-664b	bta-miR-744	bta-miR-2313-3p	bta-miR-1246	bta-miR-874
bta-miR-181a	bta-miR-150	bta-miR-15a	bta-miR-196b	bta-miR-6119-3p	bta-miR-2336

DEMs, differentially expressed miRNAs; C1, comparison between HC and HM; C2, comparison between JC and JM; C3, comparison between JC and HC; HC, Holstein colostrum–derived extracellular vesicles; HM, Holstein mature milk–derived extracellular vesicles; JC, Jersey colostrum–derived extracellular vesicles; JM, Jersey mature milk–derived extracellular vesicles.