Table 7. Gene Ontology and KEGG pathway enrichment analyses of the top 10 differentially expressed miRNAs of Holstein colostrum–derived extracellular vesicles in the comparison between Jersey colostrum– and Holstein colostrum–derived extracellular vesicles

GO ID GO term p-value Pathway ID Definition p-value
GO:0071805 Potassium ion transmembrane transport 0.004 bta04371 Apelin signaling pathway 0.008
GO:0010633 Negative regulation of epithelial cell migration 0.007 bta04211 Longevity regulating pathway 0.016
GO:0030036 Actin cytoskeleton organization 0.008 bta04151 PI3K-Akt signaling pathway 0.024
GO:0001558 Regulation of cell growth 0.008 bta00330 Arginine and proline metabolism 0.046
GO:0007346 Regulation of mitotic cell cycle 0.016
GO:0030837 Negative regulation of actin filament polymerization 0.018
GO:0071542 Dopaminergic neuron differentiation 0.021
GO:0006936 Muscle contraction 0.022
GO:0010508 Positive regulation of autophagy 0.024
GO:0042752 Regulation of circadian rhythm 0.024
Only the top 10 GO terms representing the biological process and KEGG pathway are listed in the table.
KEGG, Kyoto Encyclopedia of Genes and Genomes; PI3K, phosphatidylinositol-3-kinase.