Antibiotic Resistance in Livestock, Environment and Humans: One health perspective

Sriniwas Pandey¹, Hyunok Doo¹, Gi Beom Keum¹, Eun Sol Kim¹, Jinok Kwak¹, Sumin Ryu¹, Yejin Choi¹, Juyoun Kang¹, Sheena Kim¹, Na Rae Lee¹, Kwang Kyo Oh², Ju-Hoon Lee³^,^*, Hyeun Bum Kim¹^,^**

Author Information & Copyright ▼

¹Department of Animal Biotechnology, Dankook University, Cheonan 31116, Korea.

²Microbial Safety Division, National Institute of Agricultural Sciences, Rural Development Administration, Wanju 55365, Korea.

³Department of Food Animal Biotechnology, Department of Agricultural Biotechnology, Center for Food and Bioconvergence, Seoul National University, Seoul 08826, Korea.

^*Corresponding Author: Ju-Hoon Lee, Department of Food Animal Biotechnology, Department of Agricultural Biotechnology, Center for Food and Bioconvergence, Seoul National University, Seoul 08826, Korea, Republic of. E-mail: juhlee@snu.ac.kr.

^**Corresponding Author: Hyeun Bum Kim, Department of Animal Biotechnology, Dankook University, Cheonan 31116, Korea, Republic of. E-mail: hbkim@dankook.ac.kr.

© Copyright 2023 Korean Society of Animal Science and Technology. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Antibiotic resistance (AR) is a complex, multifaceted global health issue that poses a serious threat to livestock, humans, and the surrounding environment. It entails several elements and numerous potential transmission routes and vehicles that contribute to its development and spread, making it a challenging issue to address. AR is regarded as an One Health issue, as it has been found that livestock, human, and environmental components, all three domains are interconnected, opening up channels for transmission of antibiotic resistant bacteria (ARB). AR has turned out to be a critical problem mainly because of the overuse and misuse of antibiotics, with the anticipation of 10 million annual AR-associated deaths by 2050. The fact that infectious diseases induced by ARB are no longer treatable with antibiotics foreshadows an uncertain future in the context of health care. Hence, the One Health approach should be emphasized to reduce the impact of AR on livestock, humans, and the environment, ensuring the longevity of the efficacy of both current and prospective antibiotics.

Keywords: antibiotic resistance; livestock; human; environment; one health