Complete genome sequence of serotype 3 Streptococcus suis INT-01 isolated from a domestic pig in South Korea

Seon Young Park1,2, In Hwang Kim3, Hyun Jin Yu3, Hyoung Rok Paik3, Jee Soo Son3,*, Ji Hyung Kim1,**
Author Information & Copyright
1Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
2Division of Animal and Dairy Sciences, College of Agriculture and Life Science, Chungnam National University, Daejeon 34134, Korea.
3iNtRON Biotechnology, Inc., Seongnam 13202, Korea.
*Corresponding Author: Jee Soo Son, iNtRON Biotechnology, Inc., Seongnam 13202, Korea, Republic of. E-mail:
**Corresponding Author: Ji Hyung Kim, Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea, Republic of. E-mail:

© Copyright 2021 Korean Society of Animal Science and Technology. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received: Nov 26, 2020; Revised: Feb 08, 2021; Accepted: Feb 18, 2021

Published Online: Mar 04, 2021


Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a G + C content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an epf/mrp+/slyS. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea.

Keywords: Streptococcus suis; Pathogen; Genotype; Control strategy; Swine industry

2019 JCR Impact Factor: 1.685

The 2019 Journal Citation Reports (JCR) was announced, and the impact factor of JAST was determined to be 1.685.

We would like to ask for your continued interest and support in our journal.

Thank you.

JAST Editorial Office

I don't want to open this window for a day.